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The effectiveness of N-acetylcarnosine in diabetic retinopathy

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Category: #2 (07) 2017
Published: 18 April 2018
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Hovhannesyan A. H., Minasyan A. H., Seiranyan V. M., Hakobyan V. Ye.

Department of Ophthalmology, National Institute Health of MH RA Ophthalmology service of Erebouni Medical Center; Diagnostic center “Optomedˮ Canada − Armenia, Yerevan, Armenia 

Summary. The eye drops containing 1 % N-acetylcarnosine (Clarastill™, Bruschettini, Genoa, Italy) have been tested in patients with diabetic retinopathy in randomized blind placebo-controlled clinical trial. 

The results of the trial have shown that N-acetylcarnosine in the content of the eye drops during 6 months of using statistically significantly (versus placebo) decreases the severity of diabetic retinopathy on ETDRS scale and prevents the further development of the disease (p < 0.001). 

The early prescription of long term application of Clarastill™ eye drops is recommended for prevention of diabetic retinopathy in patients with diabetes mellitus. 

Taking into account the antioxidant, cytoprotective, eutrophic, moisturizing, lubricating properties of N-acetylcarnosine, the use of Clarastill™ eye drops is justified before and after laser coagulation of the retina; the use of the drops is also indispensable in advanced diabetic retinopathy for prevention of total blindness. 

 Keywords: diabetes, retinopathy, treatment, N-acetylcarozine, Clarastill.

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Received: 21 Sep. 2017

Published: December 2017