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The modern concept of classification, pathogenesis, clinical manifestations, diagnosis and treatment of endocrine ophthalmopathy

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Written by Super User
Category: #2 (04) 2016
Published: 13 November 2017
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 Polyakova S. I., Maletskyy A. P., Kayаli A.

The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine, Odesa, Ukraine

 Summary. A review of the literature on the classification, pathogenesis, clinical manifestations, diagnosis and treatment of endocrine ophthalmopathy (EOP). It is shown that the existing classification sufficiently reflect the degree of activity, the severity of the pathological process and compensation in orbit, and in the thyroid glande (final state substantially not considered). The clinical picture is very diverse. The main pathogenetic treatment is the use of corticosteroids as a topically (as parabulbar injection) or systemically (in the form of oral and injectable administration). Surgical treatment of EOP is generally carried out at stabilization process in the inactive phase in fibrosis. Despite all the advances in diagnosis and treatment of patients with EOP, there are still a number of outstanding issues in relation to the pathogenesis, classification, clinical course, early diagnosis, prevention and treatment of optic neuropathy, the feasibility of immunomodulation, which should determine the direction of future research in this area.

 Keywords: endocrine ophthalmopathy, classification, pathogenesis, clinical manifestations, diagnosis, treatment. 

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Received: 1 Apr. 2016

Published: July 2016