ENTER


Полный размерЗакрыть

Bacterial keratitis: epidemiological features, risk factors, etiology

Details
Written by Super User
Category: #1 (06) 2017
Published: 16 April 2018
Hits: 1983

Sakovych V.N.1, Volok S.I.2, Malik L.P.2, Isaev A.A.1


1SE «Dnepropetrovsk Medical Academy, of Ministry Health of Ukraine», Dnipro, Ukraine
2CE «Dnepropetrovsk Regional Clinical Ophthalmologic Hospital», Dnipro, Ukraine

Summary. The article is devoted to the scope and severity of bacterial keratitis of the eye, depending on risk factors (improper use of contact lenses, injury, surgery on the cornea surface skin diseases and eye adnexa, etc.) and type of pathogens (staphylococcus, pneumococci, streptococci, gonococci and pseudomonas aeruginosa). The results show the incidence of the scale compared to the epidemiological characteristics, risk factors and etiologic aspects of bacterial keratitis in the world, the severity and incidence of complications. The results presented in the literature works show an increasing number of bacterial keratitis as compared with previous years. Also in recent years, the emergence of bacterial strains that are resistant to many used in medical practice, antibiotics significantly reduces the effectiveness of the therapy. And the problem of evolutionary change agents structures and their biological properties dictate the need for clinical and microbiological monitoring, able to provide an adequate range of therapeutic and preventive measures.

Keywords: bacterial keratitis, prevalence, risk factors, etiology. 

REFERENCES

  1. Anina E.I. Pathology of the cornea of the adult population of Ukraine / E.I.Anina, K.V. Martoplyas // 12 Congress of Ophthalmologists Ukrainy. – Odessa, 2010. – P. 5–7.
  2. Miller B. Conjunctival flora in patients receiving immunosuppressive drugs / B. Miller, P.P. Ellis // Arch. Ophthalmol.- 1977. - Vol. 95, N 11. - P. 2012–2014.
  3. Makarov P.V. Complications of severe eye injury: pathogenesis, analysis of the causes, prevention and possible ways to optimize treatment outcomes: Abstract. Dis. On scientific. degree Dr. ra.med.nauk: 01.14.18 special «Ophthalmology» / P.V. Makarov. – M., 2003. – 45s.
  4. V.V. Brzhesky Complex treatment of patients with corneal ulcer, developed on the basis of a particularly severe syndrome of «dry eye» / V.V. Brzhesky, I.V. Kalinin, E.L. Efimova // New in ophthalmology. – 2006. – №3. – C. 32-34.
  5. Shaimova V.A .Risk factors in the development of purulent corneal ulcer / V.A. Shaimova // Ophthalmology at the turn of the century: mes. rep. scientific-practical. konf.-SPb., 2001. – 150 p.
  6. Maychuk Y.F. Algorithm for treatment of bacterial conjunctivitis and keratitis / Y.F. Maychuk // Directory outpatient physician. - 2005. - № 4. - C. 73-76.
  7. Dort J.K. 37 Preolisposing factors in microbial keratitis; The significans of contact- lens wearer / J.K. Dort // Can. J.Ophthalmol, 2000. - Vol.72, N12. -P. 929-930.
  8. Messmer E.M. Toxic eosinophil granule protein deposition in corneal ulcerations and scars associated with atopic keratoconjunctivitis / E.M. Messmer, C.A. May // Am. J. Ophthalmol.- 2002. - Vol. 134, N 12. - P. 816-821.
  9. Munneke R. A case of a pseudomonas corneal ulcer in an occasional use daily disposable contact lens wearer / R. Munneke, S.C. Lash, C. Prendiville // Eye Contact Lens. -2006.- Vol. 32, N 2. - P. 94-95.
  10. Dautova Z.A. Azidareg with injuries of the cornea / Z.A. Dautova, O.V. Vavilov // VII Congress of Russian Ophthalmologists: mes. dokl.- M., 2000. - Part 2. - P.72.
  11. A technique to harvest Descemet’s membrane with viable endothelial cells for selective transplantation / T. S. Ignacio [et al.] // Amer. J. Ophthalmol.- 2005. - Vol.139.-P. 325-330.
  12. The role of apoptosis in the pathogenesis of Fuchs endothelial dystrophy of the cornea / Q. J. Li [et al.] // Arch. Ophthalmol. -2001. - Vol. 119. - P. 1597-1604.
  13. Hazlett L.D. Role of innate and adaptive immunity in the pathogenesis of keratitis / L.D. Hazlett // Ocul. Immunol. Inflamm. - 2005. - Vol. 13, N 2-3. -P. 133-138.
  14. Fedunenko V.V. Ulcers of the cornea. Etiology, diagnosis and treatment in a hospital / V.V. Fedunenko // Refractive surgery and ophthalmology. - 2006. - №1. - C. 51-54.
  15. Okolov I.N. The normal flora of the conjunctiva in ophthalmic patients / Okolov I.N., P.A. Eurchenok, A.V. Vohmyakov // Oftalmol. vedomosti.- 2008 - Vol 1, № 3. - S. 18-21.
  16. Vatchenko A.B. The microflora of the conjunctiva cavity healthy eyes and pathogens of bacterial infections of the cornea / A.B. Vatchenko, V.N. Sakovich, O.N. Maksimenko // Oftalmol. zhurnal.- 2002.- № 3. - S. 53-56.
  17. Okolov I.N. The normal flora of the conjunctiva in ophthalmic patients / Okolov I.N., P.A. Eurchenok, A.V. Vohmyakov // Oftalmol. vedomosti.- 2008 - Volume 1, number 3. - S. 18-21.
  18. Okolov I.N. Microbiology eye / IN About, V.F. Danilichev // Contact Lenses. SPb LLC «RA» eyelid G «, 2008. - Chapter 7. - S. 131-155..
  19. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice / A. Thakur, R.P. Barrett, Mc.Clellan [et al.] // Curr. Eye Res. 2004. -Vol. 29, N 45. - P. 225-233.
  20. Kasparov A.A. Treatment of the most important diseases of the cornea / A.A. Kasparov // VIII Congress of Russian Ophthalmologists: mes. dokl.- M., 2005.- pp 450-451.
  21. Keay L. Epidemiology of contact lens-related inflammation and microbial keratitis: a 20- year perspective / L. Keay, F. Stapleton, O. Schein // Eye Contact Lens. – 2007. – Vol.33. – P. 346–353.
  22. Serratia corneal ulcers: a retrospective clinical study / J.H. Mah- Sadorra, D.M. Najjar, C.J. Rapuano [et al.] // Cornea. -2005. – Vol. 24, N 7. – P. 793–800.
  23. Centers for Disease Control and Prevention. Acanthamoeba keratitis multiple states, 2005- 2007 // MMWR Morb Mortal Wkly Rep. – 2007. – Vol. 56. – P. 532–534.
  24. Mason B.L. In-use study of potential bacterial contamination of ophthalmic moxifloxacin / B.L. Mason, E.C. Alfonso, D. Miller // J. Cataract. Refract. Surg. – 2005. Vol. 31, N9.- P. 1773-1776.
  25. Okolov I.N. The resistance of coagulase-negative staphylococci isolated from patients with conjunctivitis, antimicrobial / IN Around // New in ophthalmology. – 2006. – № 4. – S. 34– 36.
  26. Characteristics of Pseudomonas corneal infection related to orthokeratology / K. ArakiSasaki, I. Nishi, N. Yonemura [et al.] // Cornea. – 2005. – Vol.24.-P.861–863.
  27. Preoperative gentamicin eye drops and; chlorhexidine solution in cataract surgery. Experimental and.clinical results / P.O. Montan, I.I. Setterquist, E. Marcusson, M. Rylander [et al.] // Eur. J. Ophthalmol. – 2000. – Vol. 10, N 4. – P. 286–292.
  28. Microbial keratitis predisposing factors and morbidity / L. Keay, K. Edwards, T. Naduvilath [et al.] // Ophthalmology. – 2006. – Vol.113. – P.109–116.
  29. Egger S.F. Different techniques, of extracapsular cataract extraction: bacterial contaminationduring surgery / S.F. Egger, V. Huber-Spitzy, C. Skorpik // Graefe’s Arch. Glin. Exp. Ophthalmol. – 1994. – Vol. 232, N 5. – P. 308–311.
  30. Contribution of the cornea to cytokine levels in the whole eye induced during the early phase of Pseudomonas aeruginosa challenge / N. Cole, E.Hume, S. Khan [et al.] // Immunol. Cell Biol. 2005. – Vol. 83, N 3. – P. 301–306.
  31. Okolov I.N. The role of bacterial biofilms in the development of postoperative complications in ophthalmic surgery / I.N. Okolov, P.A. Gurchenok // Ophthalmosurgery. – 2008.- № 4. – S. 53–56.
  32. Urquhart J. Ascertaining how much compliance is enough with outpatient antibiotic regimens / J. Urquhart // Postgrad. Med. J. – 2000. – Vol. 68, Suppl. 3. – P. 49–58.

Received: 27 Oct. 2016

Published: April 2017