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- Category: #2 (10) 2019
- Published: 26 December 2019
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https://doi.org/10.30702/Ophthalmology.2019/105564
Novytskyy I.1, 2, Rudavska L.3
1Danylo Halytsky Lviv National Medical University, Lviv City Clinical Hospital No 8, Lviv, Ukraine
2Oculus Medical Center, Lviv, Ukraine
3Volyn Regional Clinical Hospital, Lutsk, Ukraine
Abstract
Introduction. The main criteria of the glaucomatous optic neuropathy stabilization are the level of the intraocular pressure (IOP), progression of the visual fields (VF) loss, morphometric data of the optic nerve head (ONH) and thickness of retinal nerve fiber layer (RNFL).
Purpose. To study the influence of the nonpenetrating deep sclerectomy with diod laser trabeculoplasty ab externo for glaucomatous optical neuropathy progression.
Methods. 94 patients (94 eyes) with primary open angle glaucoma (POAG) underwent nonpenetrating deep sclerectomy with diod laser trabeculoplasty ab externo. Maclakov’s tonometry was performed before the procedure, 7 days and every 3 months afterwards. Visual field testing was conducted before and every 4 months after the surgery. Optic coherence tomography (OCT) of the ONH and the thickness of the RNFL were analyzed twice a year.
Results. The mean IOP before the surgery was 27.1 ± 2.2 mm Hg. 1 and 2 years after the surgery IOP was 19.1 ± 1.2 mm Hg, and 19.8 ± 2.6 mm Hg accordingly. Mean defect VF before the surgery was -8.1 ± 6.9 dB, one year after the surgery -8.5 ± 6.9 dB, and -8.9 ± 7.0 dB two years after the surgery. Standard deviation of the stimulus was 6.5 ± 4.2, 6.7 ± 4.2 and 6.3 ± 4.1 dB accordingly. RNFL thickness during the first year declined from 65.3 ± 16.5 µm to 64.2 ± 16.3 µm, and during the second year – to 63.6 ± 15.9µm.
Conclusion. Nonperforatin deep sclerectomy with diod laser trabeculoplasty ab externo is an effective surgical procedure for IOP reduction for patients with POAG. VF testing and OCT of ONH and RNFL thickness have shown the slowing down the progression of the disease.
Keywords: primary open angle glaucoma, intraocular pressure, optic nerve head, nonperforating deep sclerectomy, laser trabeculoplasty, standard automated perimetry, optic coherence tomography.
REFERENCES
- Rudavska L. [Clinical effectiveness of deep nonperforating sclerectomy with simultaneous laser trabeculoplasty ab externo in patients with primary open angle glaucoma. Long term results]. Ophthlmosurgery. 2016;2:35–40. Russian.
- Pasechnikova NB, Rykov SA, Naumenko LU, et al. [Prophylactic of the blindness and low vision in Ukraine (realization of VOZ’s program “Vision-2020”)]. Current questions in ophthalmology: Proceedings of the scientific-practice conference. Dnipropetrovsk; 2009. p. 8–11. Russian.
- Ivanov DI, Nikulin ME. [Trabeculotomy ab interno as hypotensive component in combined cataract and glaucoma surgery]. National Journal of glaucoma. 2011;3:34–8. Russian.
- Barnett AG, van der Pols JC, Dobson AJ. Regression to the mean: what it is and how to deal with it. Int J. Epidemiol. 2005;34:215–20.
- Bertrand V, Fieuws S, Stalmans I, Zeyen T. Rates of visual field loss before and after trabeculectomy. Acta Ophthalmol. 2013;92:116–20.
- Bhardwaj N, Niles PI, Greenfeld DS, et al. The Impact of Surgical Intraocular Pressure Reduction on Visual Function Using Various Criteria to Defne Visual Field Progression. J Glaucoma. 2013;22 (8):632–7.
- Blackwell B, Gaasterland D, Ederer F.The Advanced Glaucoma Intervention Study (AGIS): 12. Baseline risk factors for sustained loss of visual field and visual acuity in patients with advanced glaucoma. Am J Ophthalmol. 2002;134:499–512.
- Caprioli J, De Leon JM, Azarbod P. Trabeculectomy can improve long-term visual function in glaucoma. Ophthalmology. 2016;123:117–28.
- Chauhan BC, Mikelberg FS, Balaszi AG, et al. Canadian Glaucoma Study: 2. risk factors for the progression of open-angle glaucoma. Arch Ophthalmol. 2008;126:1030–6.
- Cioffi GA, Liebmann JM. Translating the OHTS results into clinical practice. J. Glaucoma. 2002;11:375–7.
- Diniz-Filho A, Abe RY, Zangwill LM, et al. Association between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography. Ophthalmology. 2016;123:2058–65.
- American Academy of Ophthalmology. Glaucoma. Basic and Clinical Science Course, Section 10, 2011–2012. San Francisco; 2011. p. 139–58.
- Hodapp E, Parrish RK, Anderson DR. Clinical decisions in glaucoma. St Louis: Mosby; 1993. p. 52–61.
- Kotowski J, Wollstein G, Folio LS, et al. Clinical Use of OCT in Assessing Glaucoma Progression. Ophthalmic Surg Lasers Imaging. 2011;42:S6–S14.
- Karlen ME, Sanchez E, Schnyder CC, et al. Deep sclerectomy with collagen implant: medium term results. Br J Ophthalmol. 1999;83:6–11.
- Koseki N, Araie M, Shirato S, Yamamoto S. Effect of trabeculectomy on visual field performance in central 30 degrees field in progressive normal-tension glaucoma. Ophthalmology. 1997;104:197–201.
- Kotecha A, Spratt A, Bunce C, et al. Optic disc and visual field changes after trabeculectomy. Invest Ophthalmol Vis Sci. 2009;50: 4693–9.
- Leske MC, Heijl A, Hussein M, et al. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol. 2003;121:48–56.
- Migdal C, Gregory W, Hitchings R. Long-term functional outcome after early surgery compared with laser and medicine in open-angle glaucoma. Ophthalmology. 1994;101:1651–7.
- Musch DC, Gillespie BW, Lichter PR, et al. Visual field progression in the collaborative initial glaucoma treatment study the impact of treatment and other baseline factors. Ophthalmology. 2009;116 (2):200–7.
- Nouri-Mahdavi K, Brigatti L, Weitzman M, Caprioli J. Outcomes of trabeculectomy for primary open-angle glaucoma. Ophthalmology. 1995:102:1760–9.
- Pandey AN, Sujata S. Study of long term structural and functional changes in medically controlled glaucoma. Int J Ophthalmol. 2014;7:128–32.
- Sanchez E, Schnyder CC, Sickenberg M, et al. Deep sclerectomy: results with and without collagen implant. Int Ophthalmol. 1996–1997;20:157–62.
- Shigeeda T, Tomidokoro A, Araie M, et al. Long-term follow-up of visual field progression after trabeculectomy in progressive normal-tension glaucoma. Ophthalmology. 2002;109: 766–70.
- Wilson MR, Martone JF. Epidemiology of chronic open-angle glaucoma. In: Ritch R, Shield MB, Krupin T, editors. The Glaucomas. 2nd ed. St. Louis: Mosby Yearbook Inc; 1996. p. 753–68.
- Xin D, Greenstein VC, Ritch R, et al. A Comparison of Functional and Structural Measures for Identifying Progression of Glaucoma. Invest Ophthalmol Vis Sci. 2011;52 (1):519–26.
Received: 29 May 2019
Published: December 2019