Zhmud T.M.
Vinnitsa national medical university named after M.I. Pirogov, Vinnitsa, Ukraine

SUMMARY

Introduction. Research on the problems of pathological conditions of surface tissues of the eye is of particular relevance.

Aim. To study intensity of the ORP processes in a cornea at an experimental conjunctivitis and development of diabetes mellitus.

Materials and methods. For realization of experiments 52 rabbit were used, that were divided into three groups: the first – control group (8 rabbit), second – an experience group, animals, with an acute conjunctivitis (23 rabbit), is third is an experience group, animals with a conjunctivitis in the conditions of streptozotocin diabetes (21 rabbit). To investigate the tissue taken cornea and tear liquid, in that determined to activity of the redox (ORP) enzymes.

Results. In the conditions of development of experimental conjunctivitis and streptozotocin diabetes the decline of activity of the ORP enzymes is determined in tissue of cornea and increase of activity of oxidoreductases in a tear liquid.

Conclusions. It is set that at an inflammatory process in a conjunctiva in tissue of cornea for animals with streptozotocin diabetes the state of the ORP enzymes is notedly violated. In a tear liquid for animals at development of experimental conjunctivitis and diabetes mellitus the substantial increase of the ORP processes is educed, that testifies to violation to stability of cellular membrane structures.

Keywords: acute conjunctivitis, streptozotocin diabetes, ORP enzymes.

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12.04.2015